TY - GEN N2 - Despite tremendous advances in knowledge of most of the organs in our bodies, tendons largely remain a mystery. Yet tendons are implicated in a number of disorders, including over 400 that are characterized by congenital joint contractures. A condition known as arthrogryposis multiplex congenita. The aim of this research is to gain insight into various aspects of tendon biology and development, including how tendons can molecularly be distinguished from other tissues, what the distinct stages of tendon development are, how tendon progenitors transition from one developmental stage to the next, and what distinct cell populations exist in the tendon. DO - 10.6083/5999n412v DO - DOI AB - Despite tremendous advances in knowledge of most of the organs in our bodies, tendons largely remain a mystery. Yet tendons are implicated in a number of disorders, including over 400 that are characterized by congenital joint contractures. A condition known as arthrogryposis multiplex congenita. The aim of this research is to gain insight into various aspects of tendon biology and development, including how tendons can molecularly be distinguished from other tissues, what the distinct stages of tendon development are, how tendon progenitors transition from one developmental stage to the next, and what distinct cell populations exist in the tendon. AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University T1 - Single-cell transcriptomics and epigenomics analysis of tendon development ED - Schweitzer, Ronen ED - Adey, Andrew DA - 2020 AU - Sullivan, Jennifer AU - Pal, Deepanwita AU - Pryce, Brian L1 - https://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_Abstract.pdf L1 - https://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_presentation.pdf PB - Oregon Health and Science University LA - eng PY - 2020 ID - 8425 L4 - https://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_Abstract.pdf L4 - https://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_presentation.pdf KW - Musculoskeletal System KW - Tendons KW - Contracture KW - Connective Tissue KW - Single-Cell Analysis KW - transcriptomics KW - arthogryposis multiplex congenita KW - joint contracture TI - Single-cell transcriptomics and epigenomics analysis of tendon development Y1 - 2020 L2 - https://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_Abstract.pdf L2 - https://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_presentation.pdf LK - https://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_Abstract.pdf LK - https://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_presentation.pdf UR - https://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_Abstract.pdf UR - https://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_presentation.pdf ER -