000008425 001__ 8425 000008425 005__ 20240416091813.0 000008425 0247_ $$2DOI$$a10.6083/5999n412v 000008425 037__ $$aIR 000008425 041__ $$aeng 000008425 245__ $$aSingle-cell transcriptomics and epigenomics analysis of tendon development 000008425 260__ $$bOregon Health and Science University 000008425 269__ $$a2020 000008425 336__ $$aAbstract 000008425 520__ $$aDespite tremendous advances in knowledge of most of the organs in our bodies, tendons largely remain a mystery. Yet tendons are implicated in a number of disorders, including over 400 that are characterized by congenital joint contractures. A condition known as arthrogryposis multiplex congenita. The aim of this research is to gain insight into various aspects of tendon biology and development, including how tendons can molecularly be distinguished from other tissues, what the distinct stages of tendon development are, how tendon progenitors transition from one developmental stage to the next, and what distinct cell populations exist in the tendon. 000008425 540__ $$fCC BY 000008425 542__ $$fIn copyright - joint owners 000008425 650__ $$aMusculoskeletal System$$022544 000008425 650__ $$aTendons$$026832 000008425 650__ $$aContracture$$017073 000008425 650__ $$aConnective Tissue$$017025 000008425 650__ $$aSingle-Cell Analysis$$039468 000008425 6531_ $$atranscriptomics 000008425 6531_ $$aarthogryposis multiplex congenita 000008425 6531_ $$ajoint contracture 000008425 7001_ $$aSullivan, Jennifer$$uOregon Health and Science University$$041354 000008425 7001_ $$aPal, Deepanwita$$uOregon Health and Science University$$041354 000008425 7001_ $$aPryce, Brian$$uOregon Health and Science University$$041354 000008425 711__ $$aResearch Week$$uOregon Health and Science University$$d2020 000008425 7201_ $$aSchweitzer, Ronen$$7Personal 000008425 7201_ $$aAdey, Andrew$$7Personal 000008425 8564_ $$9a8218eb6-8a0c-450b-8b4b-a270ae31c098$$s127745$$uhttps://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_Abstract.pdf 000008425 8564_ $$93148d56b-912b-4646-b7bf-1d134fdba136$$s1502032$$uhttps://digitalcollections.ohsu.edu/record/8425/files/ResearchWeek.2020.Sullivan.Jennifer_presentation.pdf 000008425 905__ $$a/rest/prod/59/99/n4/12/5999n412v 000008425 980__ $$aResearch Week