TY - GEN AB - I have developed a co-mutation frequency network to infer functional redundancy between pairs of cancer genes. This analysis builds on previous work that leverages mutual exclusivity, or low co-mutation frequency, as a way to investigate the genetic mechanisms of tumorigenesis. AD - Oregon Health and Science University AU - Klocke, Christopher DA - 2020 DO - 10.6083/m039k561v DO - DOI ID - 8427 KW - Neoplasms KW - Genetics KW - Carcinogenesis KW - cancer KW - networks KW - pathway analysis L1 - https://digitalcollections.ohsu.edu/record/8427/files/ResearchWeek.2020.Klocke.Christopher.pdf L2 - https://digitalcollections.ohsu.edu/record/8427/files/ResearchWeek.2020.Klocke.Christopher.pdf L4 - https://digitalcollections.ohsu.edu/record/8427/files/ResearchWeek.2020.Klocke.Christopher.pdf LA - eng LK - https://digitalcollections.ohsu.edu/record/8427/files/ResearchWeek.2020.Klocke.Christopher.pdf N2 - I have developed a co-mutation frequency network to infer functional redundancy between pairs of cancer genes. This analysis builds on previous work that leverages mutual exclusivity, or low co-mutation frequency, as a way to investigate the genetic mechanisms of tumorigenesis. PB - Oregon Health and Science University PY - 2020 T1 - Inference of functional redundancy in cancer genes via a co-mutation frequency network TI - Inference of functional redundancy in cancer genes via a co-mutation frequency network UR - https://digitalcollections.ohsu.edu/record/8427/files/ResearchWeek.2020.Klocke.Christopher.pdf Y1 - 2020 ER -