@article{ETD,
      recid = {8596},
      author = {Hobbs, Samuel J.},
      title = {Development and function of tissue-resident memory CD8+ T  cells},
      publisher = {Oregon Health and Science University},
      school = {Ph.D.},
      address = {2020},
      number = {ETD},
      abstract = {Tissue-resident memory (TRM) CD8+ T cells permanently  reside within non-lymphoid tissues where they provide a  first-line of defense against invading pathogens. How-ever,  the mechanisms regulating their development and the  long-term functional consequences following their  activation in situ are poorly defined. Here, I use a model  of epicutaneous Vaccinia virus infection to investigate two  main research questions regarding the development and  function of TRM CD8+ T cells. I begin by describing the  role that antigen recognition within the skin  microenvironment plays in the development of TRM CD8+ T  cells. Next, I determine how repeated antigen encounters by  mature TRM CD8+ T cells impacts the composition and  function of the TRM population.},
      url = {http://digitalcollections.ohsu.edu/record/8596},
      doi = {https://doi.org/10.6083/5x21tg13g},
}