TY - THES AB - Oligodendrocytes are specialized central nervous glia that progress through distinct cellular stages, each with its own specific morphological features, specific proteins, and function. Oligodendrocyte progenitor cells (OPCs) represent the proliferative stem cell population that acts to maintain homeostatic oligodendrocyte numbers and have been shown to respond to neural activity as well as injury and disease. The role that oligodendrocytes play in signal propagation by wrapping axons in a non-conducting sheath represents the most well-known function of myelinating oligodendrocytes. AU - Foster, Antoinette DA - 2020 DO - 10.6083/4x51hj66n DO - DOI ID - 8643 KW - Myelin Sheath KW - Transcriptome KW - adaptive myelination KW - oligodenrocyte KW - glial cells KW - myelination L1 - https://digitalcollections.ohsu.edu/record/8643/files/Foster.Antoinette.2020.pdf L2 - https://digitalcollections.ohsu.edu/record/8643/files/Foster.Antoinette.2020.pdf L4 - https://digitalcollections.ohsu.edu/record/8643/files/Foster.Antoinette.2020.pdf LK - https://digitalcollections.ohsu.edu/record/8643/files/Foster.Antoinette.2020.pdf N2 - Oligodendrocytes are specialized central nervous glia that progress through distinct cellular stages, each with its own specific morphological features, specific proteins, and function. Oligodendrocyte progenitor cells (OPCs) represent the proliferative stem cell population that acts to maintain homeostatic oligodendrocyte numbers and have been shown to respond to neural activity as well as injury and disease. The role that oligodendrocytes play in signal propagation by wrapping axons in a non-conducting sheath represents the most well-known function of myelinating oligodendrocytes. PB - Oregon Health and Science University PY - 2020 T1 - Exploring the transcriptional and translational profiles of cells across the oligodendrocyte lineage TI - Exploring the transcriptional and translational profiles of cells across the oligodendrocyte lineage UR - https://digitalcollections.ohsu.edu/record/8643/files/Foster.Antoinette.2020.pdf Y1 - 2020 ER -