000000865 001__ 865 000000865 005__ 20250424232552.0 000000865 0247_ $$2DOI$$a10.6083/M4V122T8 000000865 037__ $$aETD 000000865 245__ $$aAssessing multivariate analysis of GWAS for identification of genetic variants in Alzheimer's disease 000000865 260__ $$bOregon Health and Science University 000000865 269__ $$a2012 000000865 336__ $$aThesis 000000865 502__ $$bM.S. 000000865 520__ $$aAlzheimer s Disease (AD) is the leading cause of dementia in the United States yet the genetics behind this complex disease remains unclear. With the exception of Apolipoprotein E e4 (APOE-e4), more than 40 loci have been implicated as common genetic risk factors of AD but none of these have been confirmed. We completed a genome-wide association study on 567 unrelated participants in the Alzheimer's Disease Neuroimaging Initiative ADNI data set. 000000865 542__ $$fIn copyright - single owner 000000865 650__ $$aMultivariate Analysis$$028808 000000865 650__ $$aGenetic Pleiotropy$$039320 000000865 650__ $$aGenome-Wide Association Study$$038168 000000865 650__ $$aGenomics$$033016 000000865 650__ $$aMultivariate Analysis$$028808 000000865 650__ $$aAlzheimer Disease$$014513 000000865 6531_ $$agwas 000000865 691__ $$aSchool of Medicine$$041369 000000865 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422 000000865 7001_ $$aBhatt, Priya$$uOregon Health and Science University$$041354 000000865 7201_ $$aWilmot, Beth$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor$$eMentor 000000865 8564_ $$9a6f6c285-05bb-49bd-bdc5-40c5402c5d22$$s1788916$$uhttps://digitalcollections.ohsu.edu/record/865/files/868_etd.pdf$$ePublic$$282da4772d03a513e8287724525a5467c$$31 000000865 905__ $$a/rest/prod/8k/71/nh/11/8k71nh116 000000865 909CO $$ooai:digitalcollections.ohsu.edu:865$$pstudent-work 000000865 980__ $$aBiomedical Informatics