000008740 001__ 8740
000008740 005__ 20240124114308.0
000008740 0247_ $$2DOI$$a10.6083/08612p21j
000008740 037__ $$aETD
000008740 245__ $$aPhotosensitivity and pain in traumatic brain injury
000008740 260__ $$bOregon Health and Science University
000008740 269__ $$a2020
000008740 336__ $$aDissertation
000008740 502__ $$bPh.D.
000008740 520__ $$aWe know little on why some TBIs quickly resolve, while others do not. One hint could be a common symptom shared among various chronic pain disorders and TBI: photosensitivity. Patients suffering from chronic pain syndromes often have increased sensitivity to light, as do TBI subjects. Recent research has demonstrated that nociceptive neurons in the brainstem can be activated by light, suggesting extreme photosensitivity and chronic pain are both symptoms of a dysfunctional central pain circuit. If true, photosensitivity thresholds could be used as markers of chronic pain due to altered central pain processing. This could be used not only in subjects with TBI, but other populations susceptible to centralized chronic pain, for example, individuals with Post Traumatic Stress Disorder (PTSD).
000008740 542__ $$fIn copyright - single owner
000008740 650__ $$aBrain Concussion$$015791
000008740 650__ $$aPain$$023476
000008740 6531_ $$atraumatic brain injury
000008740 6531_ $$aphotosensitivity disorder
000008740 691__ $$aSchool of Medicine$$041369
000008740 692__ $$aDepartment of Behavioral Neuroscience$$041394
000008740 7001_ $$aBalba, Nadir M.
000008740 8564_ $$910cf1fa6-7b50-41c5-92a4-e9ca0cf85acf$$s2249090$$uhttps://digitalcollections.ohsu.edu/record/8740/files/Balba.Nadir.2020.pdf
000008740 905__ $$a/rest/prod/08/61/2p/21/08612p21j
000008740 909CO $$ooai:digitalcollections.ohsu.edu:8740$$pstudent-work
000008740 980__ $$aTheses and Dissertations