@article{ETD, recid = {876}, author = {Gibbs, David}, title = {Integrated signatures of disease using network methods}, publisher = {Oregon Health and Science University}, school = {Ph.D.}, address = {2012}, number = {ETD}, abstract = {Co-expression network models help identify important biochemical pathways, biomarkers, and targets for research, but they typically focus on gene expression. In this work, co-expression network methodologies are extended to proteomics and applied to data derived from mice infected with either influenza or SARS-CoV. This work develops the methods necessary for deriving integrated network signatures of disease with an application in systems biology of infectious disease.}, url = {http://digitalcollections.ohsu.edu/record/876}, doi = {https://doi.org/10.6083/M4DR2SH4}, }