@article{ETD,
      school = {Ph.D.},
      author = {Sanford-Crane, Hannah S.},
      url = {http://digitalcollections.ohsu.edu/record/8795},
      title = {Characterization of a novel GOT2-PPARδ axis in pancreatic  ductal adenocarcinoma},
      publisher = {Oregon Health and Science University},
      abstract = {This cancer cell-intrinsic GOT2-PPARδ axis promotes  spatial restriction of both CD4+ and CD8+ T cells from the  tumor microenvironment, and fosters the immune-suppressive  phenotype of tumor-infiltrating myeloid cells. The  immune-suppressive pathophysiology of PDAC has been linked  to poor patient prognosis and makes most PDAC patients  unresponsive to immune-therapies which have proven highly  effective in cancers with improved T cell penetrance. Our  results suggest that the GOT2-PPARδ axis could be a key  player in the development of this immunological hallmark of  PDAC.},
      number = {ETD},
      doi = {https://doi.org/10.6083/6d56zx322},
      recid = {8795},
      address = {2021},
}