@article{ETD,
      school = {Ph.D.},
      author = {Cochrane, Veronica},
      url = {http://digitalcollections.ohsu.edu/record/8812},
      title = {Leptin signaling in pancreatic B-cells: a mechanism to  regulate KATP channel trafficking and B-cell electrical  activity},
      publisher = {Oregon Health and Science University},
      abstract = {Insulin is a hormone secreted by pancreatic B-cells in  response to glucose stimulation. Proper insulin secretion  keeps blood glucose in a physiological range by promoting  the uptake of glucose by insulin-sensitive target tissues.  In addition to glucose, various other metabolic and  hormonal stimuli act on B-cells to modulate insulin  secretion and maintain metabolic homeostasis. In this  thesis, leptin is shown to induce a Ca2+ influx via Src  kinase potentiation of N-Methyl-D-Aspartate (NMDA)  receptors that initiates the CaMKK?-AMPK signaling  pathways.},
      number = {ETD},
      doi = {https://doi.org/10.6083/vd66w0581},
      recid = {8812},
      address = {2021},
}