TY  - GEN
AB  - The medial olivocochlear (MOC) system aids in the prevention of age- and noise-induced hearing loss, and enhances the detection of salient sound in diverse sensory environments. While function of the MOC system has been well studied at the level of the periphery, there are gaps in our knowledge concerning the underlying central circuitry - hindering our understanding of the protective role of efferent neurons and the central mechanisms underlying their normal function. The present study used an optogenetic and electrophysiological approach to investigate excitatory responses of MOC neurons to ascending ventral cochlear nucleus (VCN) and descending inferior colliculus (IC) inputs. MOC neurons were found to be homogeneous in their spike firing properties and remarkably well suited to encoding stimulus intensity.
AU  - Romero, Gabriel E.
DA  - 2021
DO  - 10.6083/9s161691p
DO  - DOI
ID  - 8870
KW  - Electrophysiology
KW  - neuroscience
L1  - https://digitalcollections.ohsu.edu/record/8870/files/Romero.Gabriel.2021.pdf
L2  - https://digitalcollections.ohsu.edu/record/8870/files/Romero.Gabriel.2021.pdf
L4  - https://digitalcollections.ohsu.edu/record/8870/files/Romero.Gabriel.2021.pdf
LK  - https://digitalcollections.ohsu.edu/record/8870/files/Romero.Gabriel.2021.pdf
N2  - The medial olivocochlear (MOC) system aids in the prevention of age- and noise-induced hearing loss, and enhances the detection of salient sound in diverse sensory environments. While function of the MOC system has been well studied at the level of the periphery, there are gaps in our knowledge concerning the underlying central circuitry - hindering our understanding of the protective role of efferent neurons and the central mechanisms underlying their normal function. The present study used an optogenetic and electrophysiological approach to investigate excitatory responses of MOC neurons to ascending ventral cochlear nucleus (VCN) and descending inferior colliculus (IC) inputs. MOC neurons were found to be homogeneous in their spike firing properties and remarkably well suited to encoding stimulus intensity.
PB  - Oregon Health and Science University
PY  - 2021
T1  - Central circuitry underlying the medial olivocochlear efferent system
TI  - Central circuitry underlying the medial olivocochlear efferent system
UR  - https://digitalcollections.ohsu.edu/record/8870/files/Romero.Gabriel.2021.pdf
Y1  - 2021
ER  -