@article{ETD, recid = {8886}, author = {Rodriguez, Kelsie M.}, title = {Chemical tools for the elucidation of the role of PARP7 in the innate immune system}, publisher = {Oregon Health and Science University}, school = {Ph.D.}, address = {2021}, number = {ETD}, abstract = {PARPs are a family of 17 proteins that regulate a diverse range of cellular processes through the transfer of ADP-ribose from NAD+ to amino acids on protein targets, a process known as ADP-ribosylation. Identifying the protein substrates of an individual PARP family member is essential for understanding its cellular role; however, doing so remained an impracticable task until the development of chemical genetic strategies.}, url = {http://digitalcollections.ohsu.edu/record/8886}, doi = {https://doi.org/10.6083/707958363}, }