000008957 001__ 8957
000008957 005__ 20231129124949.0
000008957 0247_ $$2DOI$$a10.6083/cz30pt397
000008957 037__ $$aETD
000008957 245__ $$aThe transport mechanism of a glutamate transporter homolog
000008957 260__ $$bOregon Health and Science University
000008957 269__ $$a2021
000008957 336__ $$aDissertation
000008957 502__ $$bPh.D.
000008957 520__ $$aThe assays developed in this thesis research also offer a path to address some remaining gaps in our knowledge such as substrate assisted gate closure and the substrate release mechanism. The mechanism elucidated in this thesis should also be applicable to human glutamate transporters since the residues identified as important in GltPh are conserved in humans and in their placement in the protein's quaternary structure.
000008957 542__ $$fIn copyright - single owner
000008957 650__ $$aIons$$021017
000008957 650__ $$aMutagenesis$$029042
000008957 650__ $$aFluorescence$$019121
000008957 650__ $$aBiological Transport$$015568
000008957 650__ $$aBinding Sites$$015545
000008957 650__ $$aMolecular Conformation$$022385
000008957 691__ $$aSchool of Medicine$$041369
000008957 692__ $$aDepartment of Physiology and Pharmacology$$041442
000008957 7001_ $$aRiederer, Erika A.
000008957 8564_ $$99e8590da-2003-4c68-aec9-d8e13d1fe329$$s10551100$$uhttps://digitalcollections.ohsu.edu/record/8957/files/Riederer.Erika.2021.pdf
000008957 905__ $$a/rest/prod/cz/30/pt/39/cz30pt397
000008957 909CO $$ooai:digitalcollections.ohsu.edu:8957$$pstudent-work
000008957 980__ $$aTheses and Dissertations