@article{ETD,
      recid = {9112},
      author = {Savage, Jonathan C.},
      title = {Structural recycling  of model fluorescent  aptamers},
      publisher = {Oregon Health and Science University},
      school = {Ph.D.},
      address = {2021},
      number = {ETD},
      abstract = {This dissertation explores the capacity of direct chemical  modification of existing aptamer structures for the  discovery of novel functional applications using a closely  related family of fluorescent aptamers as a model system.  Further, this dissertation explores the merits of reusing  validated structural motifs for the accelerated discovery  of novel aptamer utility. This work additionally raises  broad questions about the influence of sequence identity  and proximity of structure in G-quadruplex-cation  interactions, and its relationship to G-Quadruplex behavior  with implications for rational tuning, and the merits of  structural recycling and functional reprogramming of  aptamers as a conceptual alternative to de novo aptamer  generation.},
      url = {http://digitalcollections.ohsu.edu/record/9112},
      doi = {https://doi.org/10.6083/3197xm90m},
}