000009149 001__ 9149
000009149 005__ 20240124114318.0
000009149 0247_ $$2DOI$$a10.6083/h415pb19t
000009149 037__ $$aETD
000009149 245__ $$aAssessing sensory and parasympathetic contributions to airway hyperreactivity using optogenetic activation and multicolor labeling of airway neurons
000009149 260__ $$bOregon Health and Science University
000009149 269__ $$a2021
000009149 336__ $$aDissertation
000009149 502__ $$bPh.D.
000009149 520__ $$aAsthma is a highly prevalent airway disease characterized by inflammation, structural remodeling of the airways and airway hyperreactivity. Despite recent advances, asthma treatment remains inadequate for many patients, because the underlying pathology of asthma remains to be fully understood. It is my hypothesis that structural changes to the sensory and parasympathetic nervous systems contribute to airway hyperreactivity associated with asthma.
000009149 542__ $$fIn copyright - single owner
000009149 650__ $$aRespiratory System$$025366
000009149 650__ $$aAsthma$$015168
000009149 650__ $$aPulmonary Eosinophilia$$024906
000009149 650__ $$aGanglia$$019377
000009149 650__ $$aAnimals$$014770
000009149 650__ $$aEpithelium$$018551
000009149 650__ $$aNeurotransmitter Agents$$030754
000009149 650__ $$aMice$$036842
000009149 650__ $$aOptogenetics$$040039
000009149 650__ $$aAutonomic Pathways$$030237
000009149 650__ $$aHumans$$020376
000009149 650__ $$aEosinophils$$018511
000009149 650__ $$aParasympathetic Nervous System$$023593
000009149 650__ $$aBronchoconstriction$$028871
000009149 6531_ $$aanimal models
000009149 691__ $$aSchool of Medicine$$041369
000009149 692__ $$aVollum Institute$$041509
000009149 7001_ $$aBowman Pincus, Alexandra
000009149 8564_ $$96963b80f-2b4d-4d00-8a34-ed4541e9093b$$s212119727$$uhttps://digitalcollections.ohsu.edu/record/9149/files/Pincus.Alexandra.2021.pdf
000009149 905__ $$a/rest/prod/h4/15/pb/19/h415pb19t
000009149 909CO $$ooai:digitalcollections.ohsu.edu:9149$$pstudent-work
000009149 980__ $$aTheses and Dissertations