000009153 001__ 9153 000009153 005__ 20240124114318.0 000009153 0247_ $$2DOI$$a10.6083/41687j07c 000009153 037__ $$aETD 000009153 245__ $$aA project to improve reactome tissue specificity via machine learning approaches using RNA-seq data 000009153 260__ $$bOregon Health and Science University 000009153 269__ $$a2021 000009153 336__ $$aDissertation 000009153 502__ $$bPh.D. 000009153 520__ $$aThe functional heterogeneity of human tissues despite their descendance from a single progenitor cell poses a substantial complication to interpretation of tissue developmental molecular studies and tissue specific diseases such as cancer. This complication significantly impedes the development of precision therapies for individual patients. 000009153 542__ $$fIn copyright - single owner 000009153 650__ $$aTissue Banks$$027120 000009153 650__ $$aProteins$$024763 000009153 650__ $$aCell Physiological Phenomena$$016292 000009153 650__ $$aBiochemistry$$015549 000009153 650__ $$aHumans$$020376 000009153 650__ $$aDeep Learning$$012734 000009153 650__ $$aNeoplasms$$022758 000009153 650__ $$aStem Cells$$026391 000009153 6531_ $$amessenger rna 000009153 6531_ $$awhole transcriptome shotgun sequencing 000009153 691__ $$aSchool of Medicine$$041369 000009153 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422 000009153 7001_ $$aGarrison Burkhart, Joshua 000009153 8564_ $$940ce2a9e-0a40-4f95-b85c-5387271bb1e8$$s10023485$$uhttps://digitalcollections.ohsu.edu/record/9153/files/Burkhart.Joshua.2021.pdf 000009153 905__ $$a/rest/prod/41/68/7j/07/41687j07c 000009153 909CO $$ooai:digitalcollections.ohsu.edu:9153$$pstudent-work 000009153 980__ $$aTheses and Dissertations