TY  - GEN
N2  - As a part of the Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) precision medicine cancer trial, serial biopsies from cancer patients are collected and analyzed to inform treatment and advance the understanding of metastatic cancer. As of now, manual segmentation is a major time limiting factor in EM image analysis for cancer tissue. In order to combat this, there are projects underway to develop machine learning algorithms to automate segmentation. Automation will hopefully allow electron microscope analysis to be a new and informative avenue for cancer research.
DO  - 10.6083/m039k5667
DO  - DOI
AB  - As a part of the Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) precision medicine cancer trial, serial biopsies from cancer patients are collected and analyzed to inform treatment and advance the understanding of metastatic cancer. As of now, manual segmentation is a major time limiting factor in EM image analysis for cancer tissue. In order to combat this, there are projects underway to develop machine learning algorithms to automate segmentation. Automation will hopefully allow electron microscope analysis to be a new and informative avenue for cancer research.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
T1  - Taking a closer look: imaging tumor microenvironments with 3D FIB-SEM reveals complex cellular interactions
DA  - 2021
AU  - Bueno, Cecilia
AU  - Riesterer, Jessica
AU  - Smith, Hannah
AU  - Machireddy, Archana
AU  - Stempinski, Erin
AU  - Loftis, Kevin
AU  - Stoltz, Kevin
AU  - Gray, Joe
L1  - https://digitalcollections.ohsu.edu/record/9197/files/Bueno-Cecilia-OHSU-ResearchWeek-2021.pdf
PB  - Oregon Health and Science University
LA  - eng
PY  - 2021
ID  - 9197
L4  - https://digitalcollections.ohsu.edu/record/9197/files/Bueno-Cecilia-OHSU-ResearchWeek-2021.pdf
KW  - Tumor Microenvironment
KW  - Image Processing, Computer-Assisted
KW  - Microscopy, Electron
KW  - Cell Communication
KW  - cancer
KW  - FIB-SEM
KW  - neoplasms
TI  - Taking a closer look: imaging tumor microenvironments with 3D FIB-SEM reveals complex cellular interactions
Y1  - 2021
L2  - https://digitalcollections.ohsu.edu/record/9197/files/Bueno-Cecilia-OHSU-ResearchWeek-2021.pdf
LK  - https://digitalcollections.ohsu.edu/record/9197/files/Bueno-Cecilia-OHSU-ResearchWeek-2021.pdf
UR  - https://digitalcollections.ohsu.edu/record/9197/files/Bueno-Cecilia-OHSU-ResearchWeek-2021.pdf
ER  -