000009197 001__ 9197
000009197 005__ 20240417091154.0
000009197 0247_ $$2DOI$$a10.6083/m039k5667
000009197 037__ $$aIR
000009197 041__ $$aeng
000009197 245__ $$aTaking a closer look: imaging tumor microenvironments with 3D FIB-SEM reveals complex cellular interactions
000009197 260__ $$bOregon Health and Science University
000009197 269__ $$a2021
000009197 336__ $$aAbstract
000009197 520__ $$aAs a part of the Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) precision medicine cancer trial, serial biopsies from cancer patients are collected and analyzed to inform treatment and advance the understanding of metastatic cancer. As of now, manual segmentation is a major time limiting factor in EM image analysis for cancer tissue. In order to combat this, there are projects underway to develop machine learning algorithms to automate segmentation. Automation will hopefully allow electron microscope analysis to be a new and informative avenue for cancer research.
000009197 540__ $$fCC BY
000009197 542__ $$fIn copyright - joint owners
000009197 650__ $$aTumor Microenvironment$$039473
000009197 650__ $$aImage Processing, Computer-Assisted$$020650
000009197 650__ $$aMicroscopy, Electron$$022283
000009197 650__ $$aCell Communication$$016275
000009197 6531_ $$acancer
000009197 6531_ $$aFIB-SEM
000009197 6531_ $$aneoplasms
000009197 7001_ $$aBueno, Cecilia$$uOregon Health and Science University$$041354
000009197 7001_ $$aRiesterer, Jessica$$uOregon Health and Science University$$041354
000009197 7001_ $$aSmith, Hannah$$uOregon Health and Science University$$041354
000009197 7001_ $$aMachireddy, Archana$$uOregon Health and Science University$$041354
000009197 7001_ $$aStempinski, Erin$$uOregon Health and Science University$$041354
000009197 7001_ $$aLoftis, Kevin$$uOregon Health and Science University$$041354
000009197 7001_ $$aStoltz, Kevin$$uOregon Health and Science University$$041354
000009197 7001_ $$aGray, Joe$$uOregon Health and Science University$$041354
000009197 711__ $$aResearch Week$$uOregon Health and Science University$$d2021
000009197 8564_ $$9bfa635d5-bfad-4818-b2ea-208591aa9748$$s74319$$uhttps://digitalcollections.ohsu.edu/record/9197/files/Bueno-Cecilia-OHSU-ResearchWeek-2021.pdf
000009197 905__ $$a/rest/prod/m0/39/k5/66/m039k5667
000009197 980__ $$aResearch Week