TY  - GEN
AB  - Obese asthmatic patients often have severe symptoms and poor responses to treatment. The molecular mechanisms of obesity-related asthma and associated airway hyperreactivity remain unclear, limiting our ability to develop new therapeutic strategies. In humans, increased airway innervation contributes to the pathogenesis of airway hyperreactivity. Here we tested if diet-induced obese mice have nerve-mediated airway hyperreactivity and increased airway sensory nerve innervation.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AU  - Calco, Gina N.
AU  - Jacoby, David
AU  - Fryer, Allison
AU  - Nie, Zhenying
DA  - 2021
DO  - 10.6083/k35694995
DO  - DOI
ID  - 9200
KW  - Obesity
KW  - Asthma
KW  - Lung Diseases
KW  - Overweight
KW  - airway hyperreactivity
L1  - https://digitalcollections.ohsu.edu/record/9200/files/Calco-Gina-OHSU-ResearchWeek-2021.pdf
L2  - https://digitalcollections.ohsu.edu/record/9200/files/Calco-Gina-OHSU-ResearchWeek-2021.pdf
L4  - https://digitalcollections.ohsu.edu/record/9200/files/Calco-Gina-OHSU-ResearchWeek-2021.pdf
LA  - eng
LK  - https://digitalcollections.ohsu.edu/record/9200/files/Calco-Gina-OHSU-ResearchWeek-2021.pdf
N2  - Obese asthmatic patients often have severe symptoms and poor responses to treatment. The molecular mechanisms of obesity-related asthma and associated airway hyperreactivity remain unclear, limiting our ability to develop new therapeutic strategies. In humans, increased airway innervation contributes to the pathogenesis of airway hyperreactivity. Here we tested if diet-induced obese mice have nerve-mediated airway hyperreactivity and increased airway sensory nerve innervation.
PB  - Oregon Health and Science University
PY  - 2021
T1  - Airway sensory nerve hyperinnervation in obese mice  with airway hyperreactivity
TI  - Airway sensory nerve hyperinnervation in obese mice  with airway hyperreactivity
UR  - https://digitalcollections.ohsu.edu/record/9200/files/Calco-Gina-OHSU-ResearchWeek-2021.pdf
Y1  - 2021
ER  -