000009200 001__ 9200
000009200 005__ 20240327111440.0
000009200 0247_ $$2DOI$$a10.6083/k35694995
000009200 037__ $$aIR
000009200 041__ $$aeng
000009200 245__ $$aAirway sensory nerve hyperinnervation in obese mice  with airway hyperreactivity
000009200 260__ $$bOregon Health and Science University
000009200 269__ $$a2021
000009200 336__ $$aAbstract
000009200 520__ $$aObese asthmatic patients often have severe symptoms and poor responses to treatment. The molecular mechanisms of obesity-related asthma and associated airway hyperreactivity remain unclear, limiting our ability to develop new therapeutic strategies. In humans, increased airway innervation contributes to the pathogenesis of airway hyperreactivity. Here we tested if diet-induced obese mice have nerve-mediated airway hyperreactivity and increased airway sensory nerve innervation.
000009200 540__ $$fCC BY
000009200 542__ $$fIn copyright - joint owners
000009200 650__ $$aObesity$$023118
000009200 650__ $$aAsthma$$015168
000009200 650__ $$aLung Diseases$$021647
000009200 650__ $$aOverweight$$036327
000009200 6531_ $$aairway hyperreactivity
000009200 691__ $$aSchool of Medicine$$041369
000009200 692__ $$aDivision of Pulmonary and Critical Care Medicine$$041467
000009200 7001_ $$aCalco, Gina N.$$uOregon Health and Science University$$041354
000009200 7001_ $$aJacoby, David$$uOregon Health and Science University$$041354
000009200 7001_ $$aFryer, Allison$$uOregon Health and Science University$$041354
000009200 7001_ $$aNie, Zhenying$$uOregon Health and Science University$$041354
000009200 711__ $$aResearch Week$$uOregon Health and Science University$$d2021
000009200 8564_ $$95d84c928-ef9c-42c4-b806-b190131d6dd8$$s42320$$uhttps://digitalcollections.ohsu.edu/record/9200/files/Calco-Gina-OHSU-ResearchWeek-2021.pdf
000009200 905__ $$a/rest/prod/k3/56/94/99/k35694995
000009200 980__ $$aResearch Week