000009211 001__ 9211 000009211 005__ 20240418092343.0 000009211 0247_ $$2DOI$$a10.6083/bc386k002 000009211 037__ $$aIR 000009211 245__ $$aTopical Timolol for treatment of chronic wounds: a systematic review 000009211 260__ $$bOregon Health and Science University 000009211 269__ $$a2021 000009211 336__ $$aAbstract 000009211 520__ $$aChronic wounds, defined as wounds which have not healed over an expected 6-week timeframe, are a common and costly burden among individuals of all ages and backgrounds. Current estimations of disease burden indicate that 2% of the United States (US) population is affected by chronic wounds. Many interventions have been proposed to address the burden of chronic wounds, including hydrocolloid gels, collagen, anti-fungal therapy, and non-adhesive bandages. There remains significant debate over which wound care products are truly efficacious. In recent years, a growing body of evidence has emerged which promotes topical timolol as effective treatment of chronic wounds. To date, however, there exists limited consensus on Timolol's efficacy and safety in this setting. This project seeks to identify and systematically review the current literature on the use of timolol in the treatment of chronic wounds. 000009211 540__ $$fCC BY 000009211 542__ $$fIn copyright - joint owners 000009211 650__ $$aDiabetic Foot$$030186 000009211 650__ $$aTimolol$$027105 000009211 650__ $$aFoot Ulcer$$029188 000009211 650__ $$aDiabetes Complications$$036146 000009211 6531_ $$achronic wounds 000009211 6531_ $$abeta adrenergic blocker 000009211 6531_ $$awound care 000009211 7001_ $$aCornwell, David$$uOregon Health and Science University$$041354 000009211 7001_ $$aChrea, Bopha$$uOregon Health and Science University$$041354 000009211 7001_ $$aMcLafferty, Robert$$uOregon Health and Science University$$041354 000009211 711__ $$aResearch Week$$uOregon Health and Science University$$d2021 000009211 8564_ $$90ef1f29c-e5e3-4280-8e8c-6f26bbac0742$$s47877$$uhttps://digitalcollections.ohsu.edu/record/9211/files/Goldstein-Zachary-OHSU-ResearchWeek-2021.pdf 000009211 905__ $$a/rest/prod/bc/38/6k/00/bc386k002 000009211 980__ $$aResearch Week