TY - GEN N2 - White matter damage after ischemic injury contributes significantly to neurological impairments. Microglia survey the environment and maintain axon's function in normal physiological conditions. In grey matter, studies showed a duality of microglia after ischemic injury: exacerbating injury through pro-inflammatory markers or promoting neuroprotection. However, the role of microglia in WM axonal injury remains to be investigated. DO - 10.6083/z890rt872 DO - DOI AB - White matter damage after ischemic injury contributes significantly to neurological impairments. Microglia survey the environment and maintain axon's function in normal physiological conditions. In grey matter, studies showed a duality of microglia after ischemic injury: exacerbating injury through pro-inflammatory markers or promoting neuroprotection. However, the role of microglia in WM axonal injury remains to be investigated. AD - Oregon Health and Science University AD - Oregon Health and Science University T1 - Sex-dependent microglia response to ischemic injury in white matter DA - 2021 AU - Nguyen, Hung AU - Baltan, Selva L1 - https://digitalcollections.ohsu.edu/record/9236/files/Nguyen-Hung-OHSU-ResearchWeek-2021.pdf PB - Oregon Health and Science University PY - 2021 ID - 9236 L4 - https://digitalcollections.ohsu.edu/record/9236/files/Nguyen-Hung-OHSU-ResearchWeek-2021.pdf KW - Stroke KW - Neuroprotection KW - Nitric Oxide Synthase KW - Microglia KW - Cerebrovascular Disorders KW - White Matter KW - microglial injury TI - Sex-dependent microglia response to ischemic injury in white matter Y1 - 2021 L2 - https://digitalcollections.ohsu.edu/record/9236/files/Nguyen-Hung-OHSU-ResearchWeek-2021.pdf LK - https://digitalcollections.ohsu.edu/record/9236/files/Nguyen-Hung-OHSU-ResearchWeek-2021.pdf UR - https://digitalcollections.ohsu.edu/record/9236/files/Nguyen-Hung-OHSU-ResearchWeek-2021.pdf ER -