000000924 001__ 924
000000924 005__ 20250424232556.0
000000924 0247_ $$2DOI$$a10.6083/M46W983Q
000000924 037__ $$aETD
000000924 245__ $$aPreparation of a genomic dataset for an investigative project : "discovery of sporatic Alzheimer's disease implicated gene variant through analysis of epistasis within pathways"
000000924 260__ $$bOregon Health and Science University
000000924 269__ $$a2013
000000924 336__ $$aCapstone
000000924 502__ $$bM.B.I.
000000924 502__ $$gBiomedical Informatics
000000924 520__ $$aToday’s genomics data requires a great deal of preprocessing before it can be utilized in analysis of biological questions. This work details the steps and requirements for processing genome‐wide association studies (GWAS) in preparation for analysis. The scripting language ‘Python’ is employed to open and read files of genomic datasets including phenotypic data, genotypic data, and demographics data, of a GWAS performed by the Harvard Brain Tissue Resource Center (HBTRC) as well as the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
000000924 540__ $$fCC BY
000000924 542__ $$fIn copyright - single owner
000000924 650__ $$aStatistics as Topic$$026381
000000924 650__ $$aElectronic Data Processing$$015239
000000924 650__ $$aMethods$$022159
000000924 650__ $$aMedical Informatics$$021938
000000924 650__ $$aGenome-Wide Association Study$$038168
000000924 650__ $$aNeuroimaging$$039660
000000924 650__ $$aGenomics$$033016
000000924 650__ $$aAlzheimer Disease$$014513
000000924 6531_ $$adata preparation
000000924 6531_ $$aorganization and management
000000924 691__ $$aSchool of Medicine$$041369
000000924 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422
000000924 7001_ $$aWilliamson, Rex$$uOregon Health and Science University$$041354
000000924 7201_ $$aWilmot, Beth$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor
000000924 8564_ $$94f95b052-d37a-4d6d-94d1-76d4cf80cb8b$$s577151$$uhttps://digitalcollections.ohsu.edu/record/924/files/927_etd.pdf$$ePublic$$28fe396ea69300cd9dd933e8e2f956f6b$$31
000000924 905__ $$a/rest/prod/s1/78/4k/78/s1784k78s
000000924 909CO $$ooai:digitalcollections.ohsu.edu:924$$pstudent-work
000000924 980__ $$aBiomedical Informatics