000009243 001__ 9243
000009243 005__ 20240305122521.0
000009243 0247_ $$2DOI$$a10.6083/ws859g38c
000009243 037__ $$aIR
000009243 041__ $$aeng
000009243 245__ $$aA comprehensive review of the therapeutic options for gastroenteropancreatic neuroendocrine tumors with a focus on PRRT and its sequencing
000009243 260__ $$bOregon Health and Science University
000009243 269__ $$a2021
000009243 336__ $$aAbstract
000009243 520__ $$aGastroenteropancreatic neuroendocrine tumors (GEP-NETs) are the most common form of neuroendocrine neoplasia, but there is no current consensus for the sequencing of approved therapies, particularly with respect to peptide receptor radionuclide therapy (PRRT). Surgical resection is recognized as the only clinically curative measure for GEP-NETs; however, given that these tumors have a propensity to metastasize and the primary tumor may, in some cases, be unresectable, various treatment options have been introduced including PRRT. This review evaluates the data supporting approved therapies for GEP-NETs and the current recommendations for therapeutic sequencing with a focus on PRRT and how sequencing might change with respect to the increasing body of literature regarding PRRT utilization.
000009243 540__ $$fCC BY
000009243 542__ $$fIn copyright - joint owners
000009243 650__ $$aNeuroendocrine Tumors$$030745
000009243 650__ $$aReceptors, Peptide$$030418
000009243 6531_ $$agastroenteropancreatic neuroendocrine tumor
000009243 6531_ $$a(177lutetium-dota(o)tyr3)octreotate
000009243 691__ $$aSchool of Medicine$$041369
000009243 7001_ $$aRaymond, Lauren M.$$uOregon Health and Science University$$041354
000009243 7001_ $$aKorzun, Tetiana$$uOregon Health and Science University$$041354
000009243 7001_ $$aKardosh, Adel$$uOregon Health and Science University$$041354
000009243 7001_ $$aKolbeck, Kenneth J.$$uOregon Health and Science University$$041354
000009243 7001_ $$aPommier, Rodney F.$$uOregon Health and Science University$$041354
000009243 7001_ $$aMittra, Erik S.$$uOregon Health and Science University$$041354
000009243 711__ $$aResearch Week$$uOregon Health and Science University$$d2021
000009243 8564_ $$9063dfd66-7810-4adf-8703-954c1811f44a$$s69182$$uhttps://digitalcollections.ohsu.edu/record/9243/files/Raymond-Lauren-OHSU-ResearchWeek-2021.pdf
000009243 905__ $$a/rest/prod/ws/85/9g/38/ws859g38c
000009243 980__ $$aResearch Week