TY  - GEN
N2  - α2δ proteins (CACNA2D1-4) are auxiliary subunits to voltage-gated calcium channels (VGCCs), and they contribute to VGCC trafficking to the plasma membrane. However, there is now evidence that their roles extend beyond VGCC-dependent function in neurons1. In fact, α2δ-1 promotes excitatory synapse formation in a calcium-independent manner. However, little is known about the potential functional redundancies of α2δ isoforms, or whether they operate pre- or postsynaptically. Thus, we investigated postsynaptic functions of the α2δ-2 proteins (CACNA2D2) in two studies.
DO  - 10.6083/d217qq29j
DO  - DOI
AB  - α2δ proteins (CACNA2D1-4) are auxiliary subunits to voltage-gated calcium channels (VGCCs), and they contribute to VGCC trafficking to the plasma membrane. However, there is now evidence that their roles extend beyond VGCC-dependent function in neurons1. In fact, α2δ-1 promotes excitatory synapse formation in a calcium-independent manner. However, little is known about the potential functional redundancies of α2δ isoforms, or whether they operate pre- or postsynaptically. Thus, we investigated postsynaptic functions of the α2δ-2 proteins (CACNA2D2) in two studies.
T1  - Functional roles for postsynaptic α2δ-2 proteins in Purkinje cells
DA  - 2021
AU  - Beeson, Kathleen A.
L1  - https://digitalcollections.ohsu.edu/record/9267/files/Beeson.Kathleen.2021.pdf
PB  - Oregon Health and Science University
PY  - 2021
ID  - 9267
L4  - https://digitalcollections.ohsu.edu/record/9267/files/Beeson.Kathleen.2021.pdf
KW  - Calcium Channels
KW  - Egtazic Acid
KW  - Protein Isoforms
KW  - Purkinje Cells
TI  - Functional roles for postsynaptic α2δ-2 proteins in Purkinje cells
Y1  - 2021
L2  - https://digitalcollections.ohsu.edu/record/9267/files/Beeson.Kathleen.2021.pdf
LK  - https://digitalcollections.ohsu.edu/record/9267/files/Beeson.Kathleen.2021.pdf
UR  - https://digitalcollections.ohsu.edu/record/9267/files/Beeson.Kathleen.2021.pdf
ER  -