@article{ETD, recid = {9285}, author = {Emerson, Dana}, title = {The role, function, and generation of Eomeshi CD8+ T Cells in OX40 and CTLA-4 targeted cancer immunotherapy}, publisher = {Oregon Health and Science University}, school = {Ph.D.}, address = {2021}, number = {ETD}, abstract = {Monoclonal antibodies targeting key receptors that inhibit T cell function such as CTLA-4 and PD-1 have demonstrated the potency of checkpoint blockade, highlighted by long-term complete responses for metastatic cancers once thought incurable. However, only a subset of patients will respond to checkpoint blockade due to a multitude of factors including an immunosuppressive tumor microenvironment and the mutational burden of the cancer.}, url = {http://digitalcollections.ohsu.edu/record/9285}, doi = {https://doi.org/10.6083/37720d444}, }