000009299 001__ 9299 000009299 005__ 20231129124947.0 000009299 0247_ $$2DOI$$a10.6083/sj139262c 000009299 037__ $$aETD 000009299 245__ $$aLost in states: effects of cocaine experience on representations supporting decision making 000009299 260__ $$bOregon Health and Science University 000009299 269__ $$a2021 000009299 336__ $$aDissertation 000009299 502__ $$bPh.D. 000009299 520__ $$aUnderstanding why and how decisions are made has been a central focus of neuroscience for several decades. The decision-making process helps humans and animals to decide the optimal course of action amongst other potential options, requiring the constant updating and integration of previous and current information to forecast future outcomes. To assist with decision making, organisms form states, each of which contains the associative information necessary for guiding behaviors under a certain circumstance. Impairments to state formation and selection can cause suboptimal decision making, leading to ineffective actions and poor outcomes. 000009299 542__ $$fIn copyright - single owner 000009299 650__ $$aPrefrontal Cortex$$029938 000009299 650__ $$aNeurosciences$$022870 000009299 650__ $$aDecision Making$$017417 000009299 650__ $$aCocaine$$016839 000009299 650__ $$aRats$$036844 000009299 691__ $$aSchool of Medicine$$041369 000009299 692__ $$aDepartment of Behavioral Neuroscience$$041394 000009299 7001_ $$aMueller, Lauren 000009299 8564_ $$951375e55-5a1d-46a0-84cc-7036ac0ebbf4$$s4603554$$uhttps://digitalcollections.ohsu.edu/record/9299/files/Mueller.Lauren.2021.pdf 000009299 905__ $$a/rest/prod/sj/13/92/62/sj139262c 000009299 909CO $$ooai:digitalcollections.ohsu.edu:9299$$pstudent-work 000009299 980__ $$aTheses and Dissertations