000000930 001__ 930
000000930 005__ 20251205092514.0
000000930 0247_ $$2DOI$$a10.6083/M4FF3QC3
000000930 037__ $$aETD
000000930 245__ $$aBioavailable vitamin D and fall risk: the osteoporotic fractures in men study
000000930 260__ $$bOregon Health and Science University
000000930 269__ $$a2013
000000930 336__ $$aThesis
000000930 502__ $$bM.P.H.
000000930 520__ $$aBioavailable 25-hydroxyvitamin D (bio25(OH)D), the fraction not bound to vitamin D binding protein, may influence neuromuscular outcomes and fall risk, but evidence is limited. This study examined associations of bio25(OH)D and total 25(OH)D with falls among 674 elderly men in the MrOS cohort. Bio25(OH)D was estimated using validated models, and falls were self-reported over 12 months. Regression analysis showed lower fall risk in the third quartile of bio25(OH)D versus the highest (RR=0.65; 95% CI: 0.45–0.96), while total 25(OH)D showed no significant association. Spline analyses suggested nonlinear relationships. Findings indicate bio25(OH)D may be more strongly linked to fall risk than total 25(OH)D, warranting further investigation.
000000930 540__ $$fCC BY
000000930 542__ $$fIn copyright - single owner
000000930 650__ $$aAging$$014358
000000930 650__ $$aRisk Factors$$025522
000000930 650__ $$aMen$$022015
000000930 650__ $$aBiological Availability$$015559
000000930 650__ $$aAccidental Falls$$011050
000000930 650__ $$aVitamin D$$027875
000000930 650__ $$a25-Hydroxyvitamin D 2$$028549
000000930 650__ $$aAged$$014351
000000930 650__ $$aVitamin D-Binding Protein$$027877
000000930 6531_ $$abioavailability
000000930 691__ $$aSchool of Medicine$$041369
000000930 692__ $$aDepartment of Public Health and Preventive Medicine$$041444
000000930 7001_ $$aGillis, Jennifer$$uOregon Health and Science University$$041354
000000930 7201_ $$aNielson, Carrie$$uOregon Health and Science University$$041354$$7Personal$$eMentor
000000930 8564_ $$97c4de28e-b2ce-4cf6-9dc1-3f0e4a97a0be$$s950468$$uhttps://digitalcollections.ohsu.edu/record/930/files/933_etd.pdf$$ePublic$$2b41551dbb52afe06e56e1c73be3e5bd8$$31
000000930 905__ $$a/rest/prod/51/38/jd/90/5138jd902
000000930 909CO $$ooai:digitalcollections.ohsu.edu:930$$pstudent-work
000000930 980__ $$aTheses and Dissertations