000000932 001__ 932
000000932 005__ 20260120144840.0
000000932 0247_ $$2DOI$$a10.6083/M4610XBP
000000932 037__ $$aETD
000000932 245__ $$aThe effect of dietary medium chain and long chain triglycerides on acyl ghrelin and relationships to hunger and satiety
000000932 260__ $$bOregon Health and Science University
000000932 269__ $$a2013
000000932 336__ $$aThesis
000000932 502__ $$bM.S.
000000932 520__ $$aGhrelin, a gut hormone that stimulates hunger, requires acylation by an 8-carbon fatty acid to become active, but its source is unclear. This randomized crossover study examined whether dietary fat influences ghrelin activation. Twenty-one participants consumed isocaloric low-fat, high-fat, and medium-chain triglyceride (MCT) diets, with ghrelin levels and hunger assessed over 13.5 hours. Acyl ghrelin was significantly higher on the MCT diet compared to other diets, and participants reported greater hunger and lower fullness. Findings suggest dietary fat, particularly MCTs, contributes to ghrelin acylation and may mediate increased hunger, offering insight into mechanisms regulating appetite.
000000932 540__ $$fCC BY
000000932 542__ $$fIn copyright - single owner
000000932 650__ $$aGhrelin$$037844
000000932 650__ $$aSatiation$$025728
000000932 650__ $$aTriglycerides$$027376
000000932 650__ $$aHunger$$020388
000000932 650__ $$aGastrointestinal Hormones$$019420
000000932 650__ $$aCross-Over Studies$$030934
000000932 650__ $$aDietary Fats$$017785
000000932 650__ $$aAppetite$$015000
000000932 691__ $$aSchool of Medicine$$041369
000000932 692__ $$aGraduate Programs in Human Nutrition$$041470
000000932 7001_ $$aJohnson, Christina$$uOregon Health and Science University$$041354
000000932 7201_ $$aGillingham, Melanie$$uOregon Health and Science University$$041354$$7Personal$$eMentor
000000932 8564_ $$929d25f9e-9490-4509-ac6e-f47f20b91977$$s4108817$$uhttps://digitalcollections.ohsu.edu/record/932/files/935_etd.pdf$$ePublic$$2ea3b714fe56d1166a3c83fffbb279f62$$31
000000932 905__ $$a/rest/prod/wh/24/6s/22/wh246s22h
000000932 909CO $$ooai:digitalcollections.ohsu.edu:932$$pstudent-work
000000932 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000000932 980__ $$aTheses and Dissertations