@article{ETD,
      recid = {933},
      author = {Phillips, Austin},
      title = {Analysis of the effect of conjugated linoleic acid on  markers of oxidative stress and inflammation in obese  individuals},
      publisher = {Oregon Health and Science University},
      school = {M.P.H.},
      address = {2013},
      number = {ETD},
      abstract = {Obesity is a global health concern linked to chronic  diseases such as diabetes, hypertension, and cancer, yet  its underlying mechanisms remain unclear. Conjugated  linoleic acid (CLA) has shown anti-obesity and anticancer  effects in animal studies and increased lean body mass in  humans. This randomized clinical trial examined the impact  of CLA supplementation (placebo, 3.2 g/day, 6.4 g/day) over  12 weeks in 48 healthy obese adults on oxidative stress and  inflammation markers. Outcomes included DNA damage,  expression of oxidative stress response genes (Nrf2, SOD1),  and serum CRP and IL-6 levels. Higher CLA doses were  significantly associated with increased CRP (p = 0.007) and  IL-6 (p = 0.02). These findings suggest CLA may elevate  inflammatory markers, warranting further research into its  role in obesity and disease risk.},
      url = {http://digitalcollections.ohsu.edu/record/933},
      doi = {https://doi.org/10.6083/M42805NS},
}