TY - GEN AB - Vocal learning is the ability to learn vocalizations through imitation, and is a rare trait shared by only a few lineages of mammals and three groups of birds. Songbirds more than any other animal model have been indispensable in elucidating the behavioral and neural mechanisms of vocal learning, and they share many key features with human speech cir-cuitry and development. The most highly studied songbird species is the zebra finch (Tae-niopygia guttata), whose song circuitry has been investigated through the many disciplines of genomics, neuroanatomy, neurophysiology, neuroendocinology, behavior, learning, and more. The brain circuitry that drives song learning and production, called the song system, is highly specialized functionally and molecularly, and strikingly sexually dimorphic. This dissertation aims to deepen our understanding of vocal learning and sexual disserentiation in the brain through the detailed molecular lens of transcriptomics. AU - Friedrich, Samantha R. DA - 2021 DO - 10.6083/xw42n8612 DO - DOI ID - 9407 KW - Brain KW - Genomics KW - Finches KW - Transcriptome KW - Ion Channels KW - Sex Differentiation L1 - https://digitalcollections.ohsu.edu/record/9407/files/Friedrich.Samantha.2021.pdf L2 - https://digitalcollections.ohsu.edu/record/9407/files/Friedrich.Samantha.2021.pdf L4 - https://digitalcollections.ohsu.edu/record/9407/files/Friedrich.Samantha.2021.pdf LK - https://digitalcollections.ohsu.edu/record/9407/files/Friedrich.Samantha.2021.pdf N2 - Vocal learning is the ability to learn vocalizations through imitation, and is a rare trait shared by only a few lineages of mammals and three groups of birds. Songbirds more than any other animal model have been indispensable in elucidating the behavioral and neural mechanisms of vocal learning, and they share many key features with human speech cir-cuitry and development. The most highly studied songbird species is the zebra finch (Tae-niopygia guttata), whose song circuitry has been investigated through the many disciplines of genomics, neuroanatomy, neurophysiology, neuroendocinology, behavior, learning, and more. The brain circuitry that drives song learning and production, called the song system, is highly specialized functionally and molecularly, and strikingly sexually dimorphic. This dissertation aims to deepen our understanding of vocal learning and sexual disserentiation in the brain through the detailed molecular lens of transcriptomics. PB - Oregon Health and Science University PY - 2021 T1 - Molecular bases of excitability and sexual dimorphism in the zebra finch song system TI - Molecular bases of excitability and sexual dimorphism in the zebra finch song system UR - https://digitalcollections.ohsu.edu/record/9407/files/Friedrich.Samantha.2021.pdf Y1 - 2021 ER -