000009407 001__ 9407 000009407 005__ 20231129124947.0 000009407 0247_ $$2DOI$$a10.6083/xw42n8612 000009407 037__ $$aETD 000009407 245__ $$aMolecular bases of excitability and sexual dimorphism in the zebra finch song system 000009407 260__ $$bOregon Health and Science University 000009407 269__ $$a2021 000009407 336__ $$aDissertation 000009407 502__ $$bPh.D. 000009407 520__ $$aVocal learning is the ability to learn vocalizations through imitation, and is a rare trait shared by only a few lineages of mammals and three groups of birds. Songbirds more than any other animal model have been indispensable in elucidating the behavioral and neural mechanisms of vocal learning, and they share many key features with human speech cir-cuitry and development. The most highly studied songbird species is the zebra finch (Tae-niopygia guttata), whose song circuitry has been investigated through the many disciplines of genomics, neuroanatomy, neurophysiology, neuroendocinology, behavior, learning, and more. The brain circuitry that drives song learning and production, called the song system, is highly specialized functionally and molecularly, and strikingly sexually dimorphic. This dissertation aims to deepen our understanding of vocal learning and sexual disserentiation in the brain through the detailed molecular lens of transcriptomics. 000009407 542__ $$fIn copyright - single owner 000009407 650__ $$aBrain$$015788 000009407 650__ $$aGenomics$$033016 000009407 650__ $$aFinches$$035808 000009407 650__ $$aTranscriptome$$039582 000009407 650__ $$aIon Channels$$021013 000009407 650__ $$aSex Differentiation$$025923 000009407 691__ $$aSchool of Medicine$$041369 000009407 692__ $$aDepartment of Behavioral Neuroscience$$041394 000009407 7001_ $$aFriedrich, Samantha R. 000009407 8564_ $$9b243d95a-afa4-4477-bda9-b489107eb89e$$s28246831$$uhttps://digitalcollections.ohsu.edu/record/9407/files/Friedrich.Samantha.2021.pdf 000009407 905__ $$a/rest/prod/xw/42/n8/61/xw42n8612 000009407 909CO $$ooai:digitalcollections.ohsu.edu:9407$$pstudent-work 000009407 980__ $$aTheses and Dissertations