000009412 001__ 9412 000009412 005__ 20240111104906.0 000009412 0247_ $$2DOI$$a10.6083/M43776R5 000009412 037__ $$aETD 000009412 245__ $$aThe cellular forms of streptolysin S and their relationship to extracellular streptolysin S 000009412 260__ $$bOregon Health and Science University 000009412 269__ $$a1972-06-01 000009412 336__ $$aThesis 000009412 502__ $$bPh.D. 000009412 520__ $$aStreptolysin S (SLS) is the most potent hemolysin known (14). It is the oxygen-stable hemolysin (104) made by Group A, C, E, G, H, and L streptococci (39). It differs from streptolysin O (SLO) in that 1) the activity once lost cannot be regenerated by reducing agents (48) (15), and 2) it is not antigenic (39). No special substances are required for SLO production (10), but SLS formation depends upon the addition of any of several different substances to the growth media or to harvested cells. The role of these additives on SLS formation or production is uncertain. A brief history of SLS will be presented to illustrate the dependence of SLS upon these additives and to present a nomenclature of SLS. 000009412 650__ $$aStreptolysins$$026456 000009412 650__ $$aBacterial Proteins$$015330 000009412 7001_ $$aCalandra, Gary B. 000009412 8564_ $$9ca1ae8ac-7f67-44ae-a6ba-7ea6ddd36e59$$s15493480$$uhttps://digitalcollections.ohsu.edu/record/9412/files/1972.calandra.gary.pdf 000009412 905__ $$a/rest/prod/5h/73/pw/84/5h73pw846 000009412 909CO $$ooai:digitalcollections.ohsu.edu:9412$$pstudent-work 000009412 980__ $$aTheses and Dissertations