000009414 001__ 9414 000009414 005__ 20240111104852.0 000009414 0247_ $$2DOI$$a10.6083/M4TT4P0B 000009414 037__ $$aETD 000009414 245__ $$aAnatomical and biochemical studies of a keratopathy induced in rats by added dietary tyrosine 000009414 260__ $$bOregon Health and Science University 000009414 269__ $$a1972-06-01 000009414 336__ $$aThesis 000009414 502__ $$bM.S. 000009414 520__ $$aTyrosinemia, also referred to in the literature as tyrosinosis or tyrosyluria, is a disease characterized by elevated levels of sermn tyrosine and by the presence of excess tyrosine, para-hydroxyphenylpyruvic acid (pHPPA), and other phenols in the urine. Among the disorders of amino acid metabolism, tyrosinemia has been studied more than others because of interest in the genetic defects of aromatic amino acid metabolism, e.g. alkaptonuria, albinism, and phenylketonuria. Attempts to simulate these disorders in animals have led to the development of experimental models for the study of tyrosinemia. 000009414 650__ $$a Tyrosinemias$$032196 000009414 650__ $$aPyruvic Acid$$031506 000009414 650__ $$aAlbinism$$014393 000009414 7001_ $$aRich, Larry F. 000009414 8564_ $$97db8384d-0cf7-4813-b4c1-4a28a854f1d6$$s3466931$$uhttps://digitalcollections.ohsu.edu/record/9414/files/1972.rich.larry.pdf 000009414 905__ $$a/rest/prod/28/01/ph/02/2801ph02v 000009414 909CO $$ooai:digitalcollections.ohsu.edu:9414$$pstudent-work 000009414 980__ $$aTheses and Dissertations