000009417 001__ 9417
000009417 005__ 20240111104904.0
000009417 0247_ $$2DOI$$a10.6083/M4FJ2DTV
000009417 037__ $$aETD
000009417 245__ $$aSolid-phase antibody radioimmunoassay of ILE5-angiotensin-I for renin activity
000009417 260__ $$bOregon Health and Science University
000009417 269__ $$a1972-06-01
000009417 336__ $$aThesis
000009417 502__ $$bM.S.
000009417 520__ $$aIn the latter part of the 1950's, Berson and Yalow demonstrated the presence of insulin antibodies in insulin resistant diabetic patients. These patients had been treated with other than species specific insulin preparations and presumably, had made antibodies against the foreign hormone. It was found that these insulin antibodies had the ability to competitively bind insulin which had been labeled with 1311 as well as unlabeled insulin. From these observations, Berson and Yalow developed the first radioirnrnunoassay (RIA) in 1959 ( 8) and presented a clinically useful method in 1960 (65).
000009417 650__ $$aInsulin Antibodies$$020874
000009417 650__ $$aDiabetes Mellitus$$017671
000009417 7001_ $$aVelander, Robert K.
000009417 8564_ $$9e1d6062f-bbb6-4788-bb38-645f4e7158a2$$s15272741$$uhttps://digitalcollections.ohsu.edu/record/9417/files/1972.velander.robert.pdf
000009417 905__ $$a/rest/prod/w0/89/2b/80/w0892b809
000009417 909CO $$ooai:digitalcollections.ohsu.edu:9417$$pstudent-work
000009417 980__ $$aTheses and Dissertations