000000942 001__ 942 000000942 005__ 20260120144840.0 000000942 0247_ $$2DOI$$a10.6083/M4WH2N14 000000942 037__ $$aETD 000000942 245__ $$aAssociations of thyroid stimulating hormone concentrations with the normal reference range on energy expenditure, macronutrient oxidation and body composition 000000942 260__ $$bOregon Health and Science University 000000942 269__ $$a2013 000000942 336__ $$aThesis 000000942 502__ $$bM.S. 000000942 520__ $$aThyroid hormones influence metabolic function, but it is unclear whether variations in thyroid-stimulating hormone (TSH) within the normal range affect metabolism. This cross-sectional study examined associations between normal-range TSH and body composition, energy expenditure, and macronutrient oxidation in 65 healthy women (euthyroid controls and L-T4 treated). Participants were grouped into low-normal (0.34–2.49 mU/L) and high-normal (2.50–5.60 mU/L) TSH categories. Measurements included total energy expenditure (doubly labeled water), resting energy expenditure (indirect calorimetry), and body composition (DEXA). Weight and BMI were significantly lower in the low-normal group (p=0.05), but no other differences or continuous associations were observed. Findings suggest TSH variation within the normal range does not meaningfully influence metabolic parameters. 000000942 540__ $$fCC BY 000000942 542__ $$fIn copyright - single owner 000000942 650__ $$aBody Composition$$015696 000000942 650__ $$aThyrotropin$$027079 000000942 650__ $$aNutritional Physiological Phenomena$$023100 000000942 650__ $$aBody Constitution$$015697 000000942 650__ $$aEnergy Metabolism$$018446 000000942 650__ $$aCross-Sectional Studies$$017206 000000942 650__ $$aThyroid Hormones$$027070 000000942 691__ $$aSchool of Medicine$$041369 000000942 692__ $$aGraduate Programs in Human Nutrition$$041470 000000942 7001_ $$aAntosik, Megan$$uOregon Health and Science University$$041354 000000942 8564_ $$948a1110a-d4bd-46f2-9c51-9ed7aa38189c$$s411662$$uhttps://digitalcollections.ohsu.edu/record/942/files/945_etd.pdf$$ePublic$$252915809c04568b13e3944041c832273$$31 000000942 905__ $$a/rest/prod/7w/62/f8/28/7w62f828h 000000942 909CO $$ooai:digitalcollections.ohsu.edu:942$$pstudent-work 000000942 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000000942 980__ $$aTheses and Dissertations