@article{ETD, school = {Ph.D.}, author = {Jacobs, David S.}, url = {http://digitalcollections.ohsu.edu/record/9443}, title = {Assessing the role of the rodent prefrontal cortex in anxiety during reward seeking}, publisher = {Oregon Health and Science University}, abstract = {The primary focus of this dissertation was to develop methods to model learning to adjust action as a function of risk using rats to assess neural representations of actions in a state of learned approach-avoidance con?ict. Once the appropriate behavioral model was developed, I focused on involvement of the prefrontal cortex (PFC) in encoding key events in behaving male and female rats in part because: 1) con?ict is believed to engage higher level control processes which are a key function of the PFC, and 2) PFC dysfunction is a common observation across psychopathologies mentioned above (Balderston, Vytal, et al., 2017; Goldstein & Volkow, 2011; Han et al., 2016; Milad & Rauch, 2007).}, number = {ETD}, doi = {https://doi.org/10.6083/0r9674565}, recid = {9443}, address = {2021}, }