Jacobs, David Moghaddam, Bita

approach-avoidance conflict conflict Anxiety Prefrontal Cortex Neuroimaging Reward Motivation Rodentia 2021 2021 The primary focus of this dissertation was to develop methods to model learning to adjust action as a function of risk using rats to assess neural representations of actions in a state of learned approach-avoidance conflict. Once the appropriate behavioral model was developed, I focused on involvement of the prefrontal cortex (PFC) in encoding key events in behaving male and female rats in part because: 1) conflict is believed to engage higher level control processes which are a key function of the PFC, and 2) PFC dysfunction is a common observation across psychopathologies mentioned above. Oregon Health and Science University Dissertation 10.6083/0r9674565 https://digitalcollections.ohsu.edu/record/9443/files/Jacobs.David.2021.pdf