TY  - GEN
AB  - Hemostasis is the process of sealing a vascular leak through concomitant activation of the blood coagulation cascade and blood platelet adhesion to and activation by the subendothelial extracellular matrix (ECM) proteins.Overall, the studies presented in this dissertation provide novel insights into the biochemical, cellular and biomechanical events governing hemostasis and thrombosis. The results from the studies could be useful in the development of devices and therapeutic strategies that improve the hemostatic safety of anticoagulant and antiplatelet agents.
AU  - Lakshmanan, Hari H.S.
DA  - 2022
DO  - 10.6083/rb68xc509
DO  - DOI
ID  - 9449
KW  - Thrombin
KW  - Microfluidics
KW  - Blood Platelets
KW  - Thrombosis
KW  - Hemostasis
KW  - Blood Coagulation
L1  - https://digitalcollections.ohsu.edu/record/9449/files/Lakshmanan.Hari.2022.pdf
L2  - https://digitalcollections.ohsu.edu/record/9449/files/Lakshmanan.Hari.2022.pdf
L4  - https://digitalcollections.ohsu.edu/record/9449/files/Lakshmanan.Hari.2022.pdf
LK  - https://digitalcollections.ohsu.edu/record/9449/files/Lakshmanan.Hari.2022.pdf
N2  - Hemostasis is the process of sealing a vascular leak through concomitant activation of the blood coagulation cascade and blood platelet adhesion to and activation by the subendothelial extracellular matrix (ECM) proteins.Overall, the studies presented in this dissertation provide novel insights into the biochemical, cellular and biomechanical events governing hemostasis and thrombosis. The results from the studies could be useful in the development of devices and therapeutic strategies that improve the hemostatic safety of anticoagulant and antiplatelet agents.
PB  - Oregon Health and Science University
PY  - 2022
T1  - Multiscale analysis of hemostasis and thrombosis
TI  - Multiscale analysis of hemostasis and thrombosis
UR  - https://digitalcollections.ohsu.edu/record/9449/files/Lakshmanan.Hari.2022.pdf
Y1  - 2022
ER  -