000009449 001__ 9449
000009449 005__ 20231129124952.0
000009449 0247_ $$2DOI$$a10.6083/rb68xc509
000009449 037__ $$aETD
000009449 245__ $$aMultiscale analysis of hemostasis and thrombosis
000009449 260__ $$bOregon Health and Science University
000009449 269__ $$a2022
000009449 336__ $$aDissertation
000009449 502__ $$bPh.D.
000009449 520__ $$aHemostasis is the process of sealing a vascular leak through concomitant activation of the blood coagulation cascade and blood platelet adhesion to and activation by the subendothelial extracellular matrix (ECM) proteins.Overall, the studies presented in this dissertation provide novel insights into the biochemical, cellular and biomechanical events governing hemostasis and thrombosis. The results from the studies could be useful in the development of devices and therapeutic strategies that improve the hemostatic safety of anticoagulant and antiplatelet agents.
000009449 542__ $$fIn copyright - single owner
000009449 650__ $$aThrombin$$027024
000009449 650__ $$aMicrofluidics$$035383
000009449 650__ $$aBlood Platelets$$015667
000009449 650__ $$aThrombosis$$027034
000009449 650__ $$aHemostasis$$020090
000009449 650__ $$aBlood Coagulation$$015652
000009449 691__ $$aSchool of Medicine$$041369
000009449 692__ $$aDepartment of Biomedical Engineering$$041397
000009449 7001_ $$aLakshmanan, Hari H.S.
000009449 8564_ $$904d90946-16b9-44a1-bc9f-1f655a948454$$s4408105$$uhttps://digitalcollections.ohsu.edu/record/9449/files/Lakshmanan.Hari.2022.pdf
000009449 905__ $$a/rest/prod/rb/68/xc/50/rb68xc509
000009449 909CO $$ooai:digitalcollections.ohsu.edu:9449$$pstudent-work
000009449 980__ $$aTheses and Dissertations