TY - GEN AB - Glial cells perform paramount functions within the nervous system, closely monitoring and regulating neurons. Indispensable roles for glia have been elucidated in most aspects of proper brain function, while they are gaining more interest in the context of neurological diseases. In this dissertation, I utilize the genetically powerful model system Drosophila melanogaster to examine injury signaling between transected neurons and the responding glia. The findings in this dissertation provide evidence for novel mechanisms involved in glial function following neuronal axotomy. AU - Richer, Petra DA - 2022 DO - 10.6083/8w32r640n DO - DOI ID - 9483 KW - Neuroglia KW - Drosophila melanogaster KW - glia cells KW - fish KW - neuronal injury KW - neuroscience L1 - https://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf L2 - https://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf L4 - https://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf LK - https://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf N2 - Glial cells perform paramount functions within the nervous system, closely monitoring and regulating neurons. Indispensable roles for glia have been elucidated in most aspects of proper brain function, while they are gaining more interest in the context of neurological diseases. In this dissertation, I utilize the genetically powerful model system Drosophila melanogaster to examine injury signaling between transected neurons and the responding glia. The findings in this dissertation provide evidence for novel mechanisms involved in glial function following neuronal axotomy. PB - Oregon Health and Science University PY - 2022 T1 - Signaling mechanisms modulating neuron-glia interactions following axonal injury TI - Signaling mechanisms modulating neuron-glia interactions following axonal injury UR - https://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf Y1 - 2022 ER -