TY - GEN N2 - Glial cells perform paramount functions within the nervous system, closely monitoring and regulating neurons. Indispensable roles for glia have been elucidated in most aspects of proper brain function, while they are gaining more interest in the context of neurological diseases. In this dissertation, I utilize the genetically powerful model system Drosophila melanogaster to examine injury signaling between transected neurons and the responding glia. The findings in this dissertation provide evidence for novel mechanisms involved in glial function following neuronal axotomy. DO - 10.6083/8w32r640n DO - DOI AB - Glial cells perform paramount functions within the nervous system, closely monitoring and regulating neurons. Indispensable roles for glia have been elucidated in most aspects of proper brain function, while they are gaining more interest in the context of neurological diseases. In this dissertation, I utilize the genetically powerful model system Drosophila melanogaster to examine injury signaling between transected neurons and the responding glia. The findings in this dissertation provide evidence for novel mechanisms involved in glial function following neuronal axotomy. T1 - Signaling mechanisms modulating neuron-glia interactions following axonal injury DA - 2022 AU - Richer, Petra L1 - https://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf PB - Oregon Health and Science University PY - 2022 ID - 9483 L4 - https://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf KW - Neuroglia KW - Drosophila melanogaster KW - glia cells KW - fish KW - neuronal injury KW - neuroscience TI - Signaling mechanisms modulating neuron-glia interactions following axonal injury Y1 - 2022 L2 - https://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf LK - https://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf UR - https://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf ER -