000009483 001__ 9483
000009483 005__ 20240124114323.0
000009483 0247_ $$2DOI$$a10.6083/8w32r640n
000009483 037__ $$aETD
000009483 245__ $$aSignaling mechanisms modulating neuron-glia interactions following axonal injury
000009483 260__ $$bOregon Health and Science University
000009483 269__ $$a2022
000009483 336__ $$aDissertation
000009483 502__ $$bPh.D.
000009483 520__ $$aGlial cells perform paramount functions within the nervous system, closely monitoring and regulating neurons. Indispensable roles for glia have been elucidated in most aspects of proper brain function, while they are gaining more interest in the context of neurological diseases. In this dissertation, I utilize the genetically powerful model system Drosophila melanogaster to examine injury signaling between transected neurons and the responding glia. The findings in this dissertation provide evidence for novel mechanisms involved in glial function following neuronal axotomy.
000009483 542__ $$fIn copyright - single owner
000009483 650__ $$aNeuroglia$$022841
000009483 650__ $$aDrosophila melanogaster$$018059
000009483 6531_ $$aglia cells
000009483 6531_ $$afish
000009483 6531_ $$aneuronal injury
000009483 6531_ $$aneuroscience
000009483 691__ $$aSchool of Medicine$$041369
000009483 692__ $$aVollum Institute$$041509
000009483 7001_ $$aRicher, Petra
000009483 8564_ $$9848904f3-3b3a-4544-a399-3f0be125f2e3$$s115049478$$uhttps://digitalcollections.ohsu.edu/record/9483/files/Richer.Petra.2022.pdf
000009483 905__ $$a/rest/prod/8w/32/r6/40/8w32r640n
000009483 909CO $$ooai:digitalcollections.ohsu.edu:9483$$pstudent-work
000009483 980__ $$aTheses and Dissertations