000009484 001__ 9484 000009484 005__ 20240125143601.0 000009484 0247_ $$2DOI$$a10.6083/c534fp59n 000009484 037__ $$aIR 000009484 041__ $$aeng 000009484 245__ $$aBad to the bone: the impact of methamphetamine on bone mineral density 000009484 260__ $$bOregon Health and Science University 000009484 269__ $$a2022 000009484 336__ $$aCapstone 000009484 502__ $$gMedicine (Undergraduate Medical Education) 000009484 502__ $$bM.D. 000009484 520__ $$aMethamphetamine is an illicit psychoactive stimulant with well recognized effects on the cardiovascular, pulmonary, and central nervous systems. The impacts of methamphetamine on these systems is well-researched. There is however limited understanding as to the effects of methamphetamine use on bone mineral density (BMD). This study found a reduction in BMD in methamphetamine users when compared to an age matched control group of patients with similar fractures and no history of methamphetamine use. Methamphetamine use may be a causative factor of, or may be correlated with, the development of osteopenia and osteoporosis. Due to its impact on BMD, methamphetamine use may increase rates of fracture and portend lower implant success rates following fracture repair. Further studies on the effectiveness of orthopaedic implants and complication rates following fracture repair are vital for improving care for this population. 000009484 540__ $$fCC BY 000009484 542__ $$fIn copyright - single owner 000009484 650__ $$aMethamphetamine$$022135 000009484 650__ $$aBone Density$$028469 000009484 6531_ $$aimaging 000009484 6531_ $$asubstance use 000009484 6531_ $$aorthopaedics 000009484 6531_ $$asurgery 000009484 691__ $$aSchool of Medicine$$041369 000009484 692__ $$aDepartment of Orthopaedics and Rehabilitation$$041436 000009484 7001_ $$aCornwell, David$$uOregon Health and Science University$$041354$$1https://orcid.org/0000-0001-6521-5318 000009484 7201_ $$aMeeker, James$$uOregon Health and Science University$$041354$$eCo-PI$$7Personal 000009484 7201_ $$aStreblow, Aaron$$uOregon Health and Science University$$041354$$eCo-PI$$7Personal 000009484 7201_ $$aBlack, Loren$$uOregon Health and Science University$$041354$$eCo-PI$$7Personal 000009484 7201_ $$aWorking, Zachary$$uOregon Health and Science University$$041354$$eCo-PI$$7Personal 000009484 8564_ $$9b25d71b6-f6ee-46c8-96a6-475f10c00b2d$$s566387$$uhttps://digitalcollections.ohsu.edu/record/9484/files/Cornwell.David.CaptionWeek.2022.pdf 000009484 905__ $$a/rest/prod/c5/34/fp/59/c534fp59n 000009484 909CO $$ooai:digitalcollections.ohsu.edu:9484$$pstudent-work 000009484 980__ $$aScholarly Project Capstones