TY - GEN N2 - An increasing amount of attention is being given to the structural and morphological aspects of biological function, and by extension the computational challenges necessary to understand them are becoming increasingly important. In cancer re-search, structural changes in the tumor microenvironment and state changes in the cells, as well as the spatial distributions of proteins at both the tissue and cellular levels are key to understanding cancer progression and evolution. Imaging modalities are integral to the development of morpho-spatial analysis because they allow us to capture the structural information in tangent to the expression information across many different biological scales with high resolution. DO - 10.6083/vd66w065f DO - DOI AB - An increasing amount of attention is being given to the structural and morphological aspects of biological function, and by extension the computational challenges necessary to understand them are becoming increasingly important. In cancer re-search, structural changes in the tumor microenvironment and state changes in the cells, as well as the spatial distributions of proteins at both the tissue and cellular levels are key to understanding cancer progression and evolution. Imaging modalities are integral to the development of morpho-spatial analysis because they allow us to capture the structural information in tangent to the expression information across many different biological scales with high resolution. T1 - Guided by objective metrics: reducing researcher bias in biomedical image analysis DA - 2022 AU - Ternes, Luke L1 - https://digitalcollections.ohsu.edu/record/9485/files/Ternes.Lukes.2022.pdf PB - Oregon Health and Science University PY - 2022 ID - 9485 L4 - https://digitalcollections.ohsu.edu/record/9485/files/Ternes.Lukes.2022.pdf KW - Deep Learning KW - image analysis KW - single cell analysis KW - feature extraction KW - multiplex imaging KW - segmentation TI - Guided by objective metrics: reducing researcher bias in biomedical image analysis Y1 - 2022 L2 - https://digitalcollections.ohsu.edu/record/9485/files/Ternes.Lukes.2022.pdf LK - https://digitalcollections.ohsu.edu/record/9485/files/Ternes.Lukes.2022.pdf UR - https://digitalcollections.ohsu.edu/record/9485/files/Ternes.Lukes.2022.pdf ER -