000009493 001__ 9493
000009493 005__ 20240124114323.0
000009493 0247_ $$2DOI$$a10.6083/70795841z
000009493 037__ $$aETD
000009493 245__ $$aDielectrophoretic isolation, quantification, and characterization of nanoparticles for early cancer detection and treatment
000009493 260__ $$bOregon Health and Science University
000009493 269__ $$a2022
000009493 336__ $$aDissertation
000009493 502__ $$bPh.D.
000009493 520__ $$aThe detection of cancer at its early stages requires the analysis of new biomarkers that are specific to the tumor and have less background than conventional biomarkers. Nanoparticles released by tumors into circulation are an important source of new biomarkers that have the potential to be sensitive enough for early stage cancer detection. These nanoparticles include exosomes, which are secreted by tumor cells at higher levels than healthy cells, contain biomolecular cargo from the tumor cells themselves, and perform critical functions in carcinogenesis.
000009493 542__ $$fIn copyright - single owner
000009493 650__ $$aNeoplasms$$022758
000009493 650__ $$aNanoparticles$$037592
000009493 650__ $$aNanoparticle Drug Delivery System$$013752
000009493 650__ $$aLiquid Biopsy$$012229
000009493 6531_ $$aimage processing
000009493 6531_ $$acancer
000009493 6531_ $$adielectrophoresis
000009493 6531_ $$acyclic immunofluorescence
000009493 691__ $$aSchool of Medicine$$041369
000009493 692__ $$aDepartment of Biomedical Engineering$$041397
000009493 7001_ $$aGustafson, Kyle T.
000009493 8564_ $$9bfcd77e4-fc2c-41dd-9377-7e06c63c39ce$$s5500434$$uhttps://digitalcollections.ohsu.edu/record/9493/files/Gustafson.Kyle.2022.pdf
000009493 905__ $$a/rest/prod/70/79/58/41/70795841z
000009493 909CO $$ooai:digitalcollections.ohsu.edu:9493$$pstudent-work
000009493 980__ $$aTheses and Dissertations