@article{ETD,
      school = {Ph.D.},
      author = {Calco, Gina N.},
      url = {http://digitalcollections.ohsu.edu/record/9495},
      title = {Nerve-mediated airway hyperreactivity in obesity-related  asthma: the central role of elevated insulin},
      publisher = {Oregon Health and Science University},
      abstract = {Obesity increases both the incidence and severity of  asthma, but the underlying mechanisms leading to the  development of obesity-related asthma remain elusive. High  insulin levels, a part of the metabolic dysfunction  frequently present in obese individuals, increase the risk  of asthma, indicating that increased insulin has a role in  the pathophysiology of obesity-related asthma. In this  dissertation I investigate the mechanisms underlying  obesity-related asthma. The findings in this dissertation  add to our understanding of the underlying mechanisms  linking insulin with airway nerve changes and excessive  bronchoconstriction. These results emphasize the need and  suggest targets for novel therapeutics specific to  obesity-related asthma for preventing and treating this  disease.},
      number = {ETD},
      doi = {https://doi.org/10.6083/474299826},
      recid = {9495},
      address = {2022},
}