TY - GEN N2 - Dry blood spot (DBS) samples can be used to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein antibodies and may offer an alternative for serologic testing of vaccinated populations. The utilization of DBS samples for measuring antibody levels in subjects vaccinated against SARS-CoV-2 has never been investigated in the literature. The aims of this project are to accurately estimate SARS-CoV-2 spike protein antibody levels in a vaccinated cohort at OHSU by utilizing DBS samples and to determine the performance characteristics of DBS samples versus serologic samples via indirect enzyme-linked immunoassays (ELISA). DO - 10.6083/b8515p10s DO - DOI AB - Dry blood spot (DBS) samples can be used to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein antibodies and may offer an alternative for serologic testing of vaccinated populations. The utilization of DBS samples for measuring antibody levels in subjects vaccinated against SARS-CoV-2 has never been investigated in the literature. The aims of this project are to accurately estimate SARS-CoV-2 spike protein antibody levels in a vaccinated cohort at OHSU by utilizing DBS samples and to determine the performance characteristics of DBS samples versus serologic samples via indirect enzyme-linked immunoassays (ELISA). AD - Oregon Health and Science University T1 - Performance of dry blood spot samples to measure SARS-CoV-2 spike protein antibodies in a vaccinated cohort ED - Curlin, Marcel ED - Lee, David X. ED - Messer, William ED - Mentor ED - Co-PI ED - Co-PI DA - 2022 AU - Goodstein, Francesca L1 - https://digitalcollections.ohsu.edu/record/9512/files/Goodstein.Francesca.CaptionWeek.2022.pdf PB - Oregon Health and Science University PY - 2022 ID - 9512 L4 - https://digitalcollections.ohsu.edu/record/9512/files/Goodstein.Francesca.CaptionWeek.2022.pdf KW - SARS-CoV-2 KW - Disease Transmission, Infectious KW - rbd spike protein KW - dry blood spots KW - indirect elisa KW - covid-19 mrna vaccine TI - Performance of dry blood spot samples to measure SARS-CoV-2 spike protein antibodies in a vaccinated cohort Y1 - 2022 L2 - https://digitalcollections.ohsu.edu/record/9512/files/Goodstein.Francesca.CaptionWeek.2022.pdf LK - https://digitalcollections.ohsu.edu/record/9512/files/Goodstein.Francesca.CaptionWeek.2022.pdf UR - https://digitalcollections.ohsu.edu/record/9512/files/Goodstein.Francesca.CaptionWeek.2022.pdf ER -