000009512 001__ 9512
000009512 005__ 20240125143604.0
000009512 0247_ $$2DOI$$a10.6083/b8515p10s
000009512 037__ $$aIR
000009512 245__ $$aPerformance of dry blood spot samples to measure SARS-CoV-2 spike protein antibodies in a vaccinated cohort
000009512 260__ $$bOregon Health and Science University
000009512 269__ $$a2022
000009512 336__ $$aCapstone
000009512 502__ $$gMedicine (Undergraduate Medical Education)
000009512 502__ $$bM.D.
000009512 520__ $$aDry blood spot (DBS) samples can be used to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein antibodies and may offer an alternative for serologic testing of vaccinated populations. The utilization of DBS samples for measuring antibody levels in subjects vaccinated against SARS-CoV-2 has never been investigated in the literature. The aims of this project are to accurately estimate SARS-CoV-2 spike protein antibody levels in a vaccinated cohort at OHSU by utilizing DBS samples and to determine the performance characteristics of DBS samples versus serologic samples via indirect enzyme-linked immunoassays (ELISA).
000009512 540__ $$fCC BY
000009512 650__ $$aSARS-CoV-2$$013516
000009512 650__ $$aDisease Transmission, Infectious$$030908
000009512 6531_ $$arbd spike protein
000009512 6531_ $$adry blood spots
000009512 6531_ $$aindirect elisa
000009512 6531_ $$acovid-19 mrna vaccine
000009512 691__ $$aSchool of Medicine$$041369
000009512 692__ $$aDepartment of Molecular Microbiology and Immunology$$041429
000009512 7001_ $$aGoodstein, Francesca$$uOregon Health and Science University$$041354
000009512 7201_ $$aCurlin, Marcel$$eMentor$$7Personal$$uOregon Health and Science University$$041354
000009512 7201_ $$aLee, David X.$$eCo-PI$$7Personal$$uOregon Health and Science University$$041354
000009512 7201_ $$aMesser, William$$eCo-PI$$7Personal$$uOregon Health and Science University$$041354
000009512 8564_ $$9dfe99f4d-1a61-42f9-baad-4a62b8d08435$$s617573$$uhttps://digitalcollections.ohsu.edu/record/9512/files/Goodstein.Francesca.CaptionWeek.2022.pdf
000009512 905__ $$a/rest/prod/b8/51/5p/10/b8515p10s
000009512 909CO $$ooai:digitalcollections.ohsu.edu:9512$$pstudent-work
000009512 980__ $$aScholarly Project Capstones