@article{IR, author = {Dimagiba, Yvonne T. and Tripathy, Sudeshna and Ellery, Stacey J. and Snow, Rod J. and Walker, David W. and Sherman, Larry S. and Kelleher, Meredith A.}, url = {http://digitalcollections.ohsu.edu/record/9529}, title = {Maternal and perinatal outcomes of maternal creatine supplementation as a therapy for neonatal encephalopathy}, publisher = {Oregon Health and Science University}, abstract = {Hypoxic ischemic encephalopathy (HIE) occurs in ~4 per 1000 live term births. Infants that receive current treatments may still develop adverse neurologic outcomes. Maternal gestational creatine supplementation has been proposed as a potential prophylactic neuroprotective therapy, with evidence of reduction in perinatal brain injury in rodent and sheep studies. The current study aims to characterize aspects of creatine synthesis, metabolism, and transport in gestational and neonatal tissues following maternal oral creatine supplementation.}, number = {IR}, doi = {https://doi.org/10.6083/hq37vp30d}, recid = {9529}, address = {2022}, }