TY  - GEN
N2  - Hypoxic ischemic encephalopathy (HIE) occurs in ~4 per 1000 live term births. Infants that receive current treatments may still develop adverse neurologic outcomes. Maternal gestational creatine supplementation has been proposed as a potential prophylactic neuroprotective therapy, with evidence of reduction in perinatal brain injury in rodent and sheep studies. The current study aims to characterize aspects of creatine synthesis, metabolism, and transport in gestational and neonatal tissues following maternal oral creatine supplementation.
DO  - 10.6083/hq37vp30d
DO  - DOI
AB  - Hypoxic ischemic encephalopathy (HIE) occurs in ~4 per 1000 live term births. Infants that receive current treatments may still develop adverse neurologic outcomes. Maternal gestational creatine supplementation has been proposed as a potential prophylactic neuroprotective therapy, with evidence of reduction in perinatal brain injury in rodent and sheep studies. The current study aims to characterize aspects of creatine synthesis, metabolism, and transport in gestational and neonatal tissues following maternal oral creatine supplementation.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Hudson Medical Research Institute
AD  - Deakin University
AD  - RMIT University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
T1  - Maternal and perinatal outcomes of maternal creatine supplementation as a therapy for neonatal encephalopathy
DA  - 2022
AU  - Dimagiba, Yvonne T.
AU  - Tripathy, Sudeshna
AU  - Ellery, Stacey J.
AU  - Snow, Rod J.
AU  - Walker, David W.
AU  - Sherman, Larry S.
AU  - Kelleher, Meredith A.
L1  - https://digitalcollections.ohsu.edu/record/9529/files/Dimagiba-Yvonne-OHSU-ResearchWeek-2022.pdf
PB  - Oregon Health and Science University
LA  - eng
PY  - 2022
ID  - 9529
L4  - https://digitalcollections.ohsu.edu/record/9529/files/Dimagiba-Yvonne-OHSU-ResearchWeek-2022.pdf
KW  - Creatine
KW  - Cerebral Palsy
KW  - Pregnancy
KW  - Premature Birth
KW  - Hypoxia-Ischemia, Brain
KW  - Hypoxia, Brain
KW  - hypoxic-ischemic encephalopathy
TI  - Maternal and perinatal outcomes of maternal creatine supplementation as a therapy for neonatal encephalopathy
Y1  - 2022
L2  - https://digitalcollections.ohsu.edu/record/9529/files/Dimagiba-Yvonne-OHSU-ResearchWeek-2022.pdf
LK  - https://digitalcollections.ohsu.edu/record/9529/files/Dimagiba-Yvonne-OHSU-ResearchWeek-2022.pdf
UR  - https://digitalcollections.ohsu.edu/record/9529/files/Dimagiba-Yvonne-OHSU-ResearchWeek-2022.pdf
ER  -